Papaverine Hydrochloride and Experimental Hemorrhagic Cerebral Arterial Spasm

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Papaverine hydrochloride and experimental hemorrhagic cerebral arterial spasm.

Papaverine Hydrochloride and Experimental Hemorrhagic Cerebral A rterial Spasm • Chronic hemorrhagic spasm of the basilar artery was produced in beagle dogs by introducing blood into the cisterna magna. Spasm was evaluated by means of vertebral angiography. Papaverine hydrochloride was administered intravenously, intracisternally as well as intra-arterially. The intracisternal route was the mor...

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A model for experimental cerebral arterial spasm.

A Model for Experimental Cerebral A rterial Spasm • Vasospasm of the basilar artery of the dog was induced by subarachnoid injection of arterial blood through the cisterna magna. Cerebral angiography was employed to evaluate quantitative assessment of the spasm. Chronic vasospasm was successfully induced in 100% of surviving dogs. Biphasic vasoconstriction was observed. The acute phase occurred...

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Photostabilization of papaverine hydrochloride solutions.

Abstract: The stability of aqueous and non-aqueous papaverine hydrochloride solutions exposed to the UV radiation is poor. In order to enhance its photo-stability suitable light absorbers may be used. There werefour photo-protectors considered in this work: 4-aminobenzoic acid, sodium benzoate, methyl 4-hydroxybenzoate and propyl 4-hydroxybenzoate, whose UV absorption spectra characteristics ma...

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Intraarterial infusion of papaverine in experimental cerebral vasospasm.

PURPOSE To determine the effectiveness of intraarterial infusion of papaverine hydrochloride (PPV) in an experimental model of cerebral vasospasm and to measure the mean blood flow velocity of the middle cerebral artery (MCA). METHODS Seven Japanese monkeys were divided into three groups: those studied 3 days-after surgery (the third-day group, n = 3); those studied 7 days after surgery (the ...

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Transcavernous Installation of Papaverine Hydrochloride in Impotence

Impotence is syndrome involving the interaction of psychogenic, hormonal, neurological, arterial, venous & sinusoidal factors. Management of impotence has evolved from a time-born pattern of sympathetic discussion and empiric use of medication to a scientifically planned diagnostic protocol and specific treatment regime. The present study was undertaken to assess the effects of pharmacologicall...

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ژورنال

عنوان ژورنال: Stroke

سال: 1972

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.3.1.27